Automated Assays Automated Assays

Public catalogue

What the corpus needs, and what this platform can run.

The corpus reads research papers and records the analysis each one used. This catalogue joins that to the assay definitions this platform holds, so the gap between what science needs and what can be run is visible rather than asserted.

Corpus snapshot ba34b49490d9bfaf · run run-20261023T122449232913 · published 2026-10-23T12:25:29.022232+00:00

5,529
Papers analysed

The corpus sample read for the method each paper used and for where its data lives.

303
Papers with the method pinned down

Of those, the analysis was identified precisely enough to route without a person deciding.

20
Families of method

The methods cluster into families — group comparison, incidence rates, survival analysis — and each family needs a known set of analysis operations.

8
Assay definitions held

Versioned programmes the platform can run today, from qPCR measurement to compound-response screens to statistical operations.

2
Families runnable end to end

One-way analysis of variance and incidence-rate modelling. Both proved against synthetic data with known answers, both replayable from their evidence bundle.

24
Analysis operations still to write

The corpus names the operations it needs and the platform has not implemented yet. They are ranked by how many papers each one unlocks and written in that order.

The method families

Each family is a group of papers that share a kind of analysis. A family is runnable here when this platform holds an assay definition that covers every operation the family needs.

Family Papers Analysis it needs Status here
Regression modelling regression_modelling 87 glm_logit_fit ols_fit regression_modelling_mixed_effects regression_modelling_negative_binomial regression_modelling_poisson Not built here
Group comparison group_comparison 43 group_comparison_anova group_comparison_mann_whitney group_comparison_wilcoxon student_t Partly built group-comparison-analysis
Survival analysis survival_analysis 40 cox_ph logrank_test survival_km Not built here
Categorical (contingency table) analysis contingency_analysis 24 chi_square_test contingency_analysis_fisher_exact Not built here
Image analysis / quantification image_quantification 22 image_quantification_densitometry image_quantification_segmentation Not built here
Machine learning machine_learning 19 machine_learning_decision_tree machine_learning_gradient_boosting machine_learning_random_forest machine_learning_support_vector_machine Not built here
Epidemiological rate modelling epidemiological_modelling 16 epidemiological_modelling_incidence_rate Runnable end to end incidence-rate-analysis
Principal component analysis principal_component_analysis 16 pca_fit Not built here
Diagnostic test evaluation diagnostic_evaluation 13 diagnostic_evaluation_roc Not built here
Meta-analysis / evidence synthesis meta_analysis 12 fixed_effects_pool random_effects_pool Not built here
Correlation analysis correlation_analysis 11 pearson_r spearman_rho Not built here
Genetic association (GWAS / linkage / MR) genetic_association 9 genetic_association_linkage gwas_locus_scan mr_estimate Not built here
Sequence alignment / homology sequence_alignment 8 sequence_alignment_blast sequence_alignment_msa Not built here
Multi-omics integration multi_omics_integration 7 multi_omics_integration_pathway_progeny Not built here
Network / pathway analysis network_analysis 7 network_analysis_centrality network_analysis_ppi_network pathway_enrich Not built here
Clustering clustering 5 hierarchical_cluster kmeans_fit Not built here
Flow cytometry analysis flow_cytometry_analysis 2 flow_cytometry_analysis_mfi Not built here
Differential expression analysis differential_expression 1 differential_expression_limma_voom Not built here
Model calibration / clinical utility model_calibration 1 model_calibration_decision_curve Not built here
Reliability and agreement analysis reliability_analysis 1 cronbach_alpha Not built here

The build list

Every analysis operation the corpus names, in the order this platform intends to write them: by the number of papers each one unlocks on its own. The two at the top are written and proved.

Operation Papers that need it Papers it unlocks alone Built here
group_comparison_anova 27 23 Yes
epidemiological_modelling_incidence_rate 16 15 Yes
image_quantification_segmentation 17 14 Not yet, and not in the corpus catalogue
diagnostic_evaluation_roc 13 12 Not yet, and not in the corpus catalogue
contingency_analysis_fisher_exact 9 7 Not yet, and not in the corpus catalogue
machine_learning_support_vector_machine 11 6 Not yet, and not in the corpus catalogue
multi_omics_integration_pathway_progeny 7 6 Not yet, and not in the corpus catalogue
sequence_alignment_blast 6 6 Not yet, and not in the corpus catalogue
group_comparison_mann_whitney 9 5 Not yet, and not in the corpus catalogue
student_t 6 5 Not yet, and not in the corpus catalogue
machine_learning_random_forest 9 4 Not yet, and not in the corpus catalogue
image_quantification_densitometry 5 4 Not yet, and not in the corpus catalogue
network_analysis_ppi_network 4 4 Not yet, and not in the corpus catalogue
group_comparison_wilcoxon 5 3 Not yet, and not in the corpus catalogue
regression_modelling_mixed_effects 4 3 Not yet, and not in the corpus catalogue
machine_learning_decision_tree 4 2 Not yet, and not in the corpus catalogue
fixed_effects_pool 2 2 Not yet, and not in the corpus catalogue
flow_cytometry_analysis_mfi 2 2 Not yet, and not in the corpus catalogue
regression_modelling_poisson 2 2 Not yet, and not in the corpus catalogue
sequence_alignment_msa 2 2 Not yet, and not in the corpus catalogue
genetic_association_linkage 4 1 Not yet, and not in the corpus catalogue
regression_modelling_negative_binomial 2 1 Not yet, and not in the corpus catalogue
differential_expression_limma_voom 1 1 Not yet, and not in the corpus catalogue
model_calibration_decision_curve 1 1 Not yet, and not in the corpus catalogue
network_analysis_centrality 1 1 Not yet, and not in the corpus catalogue
machine_learning_gradient_boosting 2 0 Not yet, and not in the corpus catalogue

What this catalogue does not tell you

  • It counts papers, not verified replications. No dataset has been downloaded, access-checked or licence-read, so a paper being in the corpus says nothing about whether its data can be used.
  • "Runnable end to end" means the analysis operation is implemented, proved against synthetic data and replayable from its evidence bundle. It does not mean a physical assay has been run at a facility.
  • The facilities named in the provider registry have not been contacted. Their access state stays "named, not verified" and any rate shown is a published rate, never a quote.
  • The corpus is a sample of the published literature, not the literature. It covers the methods it could determine, and it says so on the process map for every paper it could not.

Caveats published with this snapshot

  • Method extraction is rule-based and has no hand-judged accuracy sample. Evidence bands order textual support; method agreement intervals are null (n=0), never probabilities. Work-type validation does not validate methods.
  • Operation coverage describes only explicitly named methods. It does not prove a complete protocol, compatible parameters, successful compilation or re-execution. Unrecognised or ambiguous methods require review.
  • Data reachability is a textual accession or public-data statement. No dataset was downloaded or checked for access, completeness or licence.
  • Capabilities are planning states seeded from the dated equipment register. No bench ownership, completed quote or partner booking is inferred. Procurement counts are dependencies, not guaranteed replications or financial returns.
  • Tier and blocker counts are deterministic assessments of this corpus, not measured agreement. R3 is reserved for procurement; unresolved methods and data require human work (R4). The most restrictive axis wins, with capability, method, data as tie-breaks. Resolving one blocker can leave another at the same tier.